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Are there any type 2 diabetes drugs that can help people lose weight and lower their blood sugar? Are there side effects?

Answer From M. Regina Castro, M.D.

There''t insulin. These medications not only improve blood sugar control but may also lead to weight loss.

Depending on the medication and the dose, weight loss may average about 3 to 5.5 pounds (1.5 kilograms, or kg, to 2.5 kg) when using these drugs. If you''s not clear whether these benefits are from the medicine or the weight loss.

The downside to these drugs is that they have to be taken by injection, and they also have a risk of side effects, some serious. The more common side effects may improve after you''re taking another medication known to lower blood sugar.

This class of drugs isn''t known. They''ve had pancreatitis.

The drugs already discussed are designed for people who have type 2 diabetes. There is also a drug that contains a higher dose of liraglutide (Saxenda) that''t have diabetes.

reverses diabetes type 2 mellitus with hyperglycemia (🔴 explained) | reverses diabetes type 2 need insulinhow to reverses diabetes type 2 for If you have diabetes and wonder if one of these drugs may be helpful for you, talk to your doctor.


M. Regina the 1 last update 27 May 2020 Castro, M.D. M. Regina Castro, M.D.

May the 1 last update 27 May 2020 11, 2018May 11, 2018
  1. Ryan D, et al. GLP-1 receptor agonists: Nonglycemic clinical effects in weight loss and beyond. Obesity. 2015;23:1119.
  2. Dungan K, et al. Glucagon-like peptide-1-based therapies for the treatment of type 2 diabetes mellitus. Accessed April 13, 2018.
  3. Burcelin R, et al. Harnessing glucagon-like peptide-1 receptor agonists for the pharmacological treatment of overweight and obesity. Obesity Reviews. 2017;18:87.
  4. Perreault L. Obesity in adults: Drug therapy. Accessed April 13, 2018.
  5. Trujillo JM, et al. GLP-1 receptor agonists: A review of head-to-head clinical studies. Therapeutic Advances in Endocrinology and Metabolism. 2015;6:19.
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